There are no known side effects of laser treatment for toenail fungus, including pain. Depending on the laser treatment, you might feel a “heating” sensation in your toes. The energy bursts from the laser can be warm and make the toes feel hot. For the vast majority of people, this is not painful or even terribly uncomfortable. Some people don’t feel anything at all. A small minority may feel slight discomfort, but if you let our team at Podiatry Associates, P.C. know, we’ll do what we can to make it as comfortable as possible.